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Chronic liver diseases are characterised by persistent hepatocellular injury, which triggers a proinflammatory state capable of progressing to fibrosis, cirrhosis, and liver failure

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Clinical Trials and Safety Data GLP-1s have been studied in large-scale trials for over a decade

- Sanofi - Orexigen Therapeutics - Amgen - Johnson & Johnson - Abbott Laboratories - Takeda Pharmaceutical Company - Zafgen - Currax Pharmaceuticals - Rhythm Pharmaceuticals Key Developments In September 2025, Eli Lilly announced plans to launch its experimental weight-loss pill, orforglipron, in India

PMID 29318504